BIBAC team
The BIBAC team (“Biomolecule Interaction with Biomimetic soft matter and Analytical Chemistry”) develops analytical tools and strategies in nuclear magnetic resonance (NMR) and mass spectrometry (MS), possibly coupled with separation techniques, such as capillary electrophoresis and high-performance liquid chromatography. The team primarily focuses most of its research activities on the chemistry-biology interface.
The researchers are particularly interested in the oxidation phenomena induced by reactive oxygen species. This involves elucidating oxidation mechanisms of molecules of biological interest, studying peptide-lipid oxidative interactions and exploring the response from the metabolome to a stimulus (inflammation, oxidative stress, etc.), linked to neurodegenerative diseases.
The team also develops original analytical methodologies for the study of complex assemblies and their chemical or photochemical modification. These methodologies play a crucial role for the development of new analytical strategies.
Research topics
Analytical tools applied to oxidation phenomenon & to metabolism
Analytical methodologies for studying complex assemblies
Team members
permanent members
temporary members on average per year
Faculty staff
Engineer assistant
Team publications
This list of publications is uploaded directly from the BIBAC team’s HAL collection.
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- Hai Yen Ta, Christophe Déjugnat, Stéphane Balayssac, Fabrice Collin, Stéphanie Balor, et al.. Separation of unsaturated C18 fatty acids using perfluorinated-micellar electrokinetic chromatography: II) role of nano-structuration. Journal of Molecular Liquids, 2022, 360, pp.119478. ⟨10.1016/j.molliq.2022.119478⟩. ⟨hal-03719917⟩
- Hai Yen Ta, Lucie Perquis, Stéphane Balayssac, Christophe Dejugnat, Alexandre Wodrinski, et al.. Separation of unsaturated C18 fatty acids using perfluorinated‐micellar electrokinetic chromatography: I) Optimization and separation process. Electrophoresis, 2022, ⟨10.1002/elps.202200151⟩. ⟨hal-03864965⟩
- Nadiia Yakovenko, Baptiste Amouroux, Magali Albignac, Fabrice Collin, Clément Roux, et al.. Top-down synthesis of luminescent microplastics and nanoplastics by incorporation of upconverting nanoparticles for environmental assessment. Environmental science.Nano, 2022, 9 (7), pp.2453-2463. ⟨10.1039/d2en00029f⟩. ⟨hal-03694746⟩
- Alexis Piedrafita, Stéphane Balayssac, Audrey Casemayou, Jean Sébastien Saulnier-Blache, Alexandre Lucas, et al.. Hepatocyte nuclear factor‐1β shapes the energetic homeostasis of kidney tubule cells. FASEB Journal, 2021, 35 (11), pp.e21931. ⟨10.1096/fj.202100782RR⟩. ⟨inserm-03531997⟩
- Chantal Galaup, François Couderc, Véronique Gilard, Fabrice Collin, Claude Picard. Luminescent lanthanide complexes for reactive oxygen species biosensing and possible application in Alzheimer’s diseases. FEBS Journal, 2021, ⟨10.1111/febs.15859⟩. ⟨hal-03240518⟩
- Petr Tůma, Blanka Sommerová, Dušan Koval, François Couderc. Electrophoretic Determination of Symmetric and Asymmetric Dimethylarginine in Human Blood Plasma with Whole Capillary Sample Injection. International Journal of Molecular Sciences, 2021, Capillary Electrophoresis for Amino Acids Analysis: From Analytical Development to Biomedical Application, 22 (6), pp.2970. ⟨10.3390/ijms22062970⟩. ⟨hal-03221992⟩
- Hai Yen Ta, Lucie Perquis, Cédric Sarazin, Bruno Guiard, Varravaddheay Ong-Meang, et al.. 3‐(4‐Carboxybenzoyl)quinoline‐2‐carboxaldehyde labeling for direct analysis of amino acids in plasma is not suitable for simultaneous quantification of tryptophan, tyrosine, valine, and isoleucine by CE/fluorescence. Electrophoresis, 2021, ⟨10.1002/elps.202000263⟩. ⟨hal-03139489⟩
- Thouria Bourhim, Myra Villareal, François Couderc, Abdellatif Hafidi, Hiroko Isoda, et al.. Melanogenesis Promoting Effect, Antioxidant Activity, and UPLC-ESI-HRMS Characterization of Phenolic Compounds of Argan Leaves Extract. Molecules, 2021, 26 (2), pp.371. ⟨10.3390/molecules26020371⟩. ⟨hal-03139490⟩
- Tomás Allen Rush, Virginie Puech Pagès, Adeline Bascaules, Patricia Jargeat, Fabienne Maillet, et al.. Lipo-chitooligosaccharides as regulatory signals of fungal growth and development. Nature Communications, 2020, 11, pp.3897. ⟨10.1038/s41467-020-17615-5⟩. ⟨hal-02916284⟩
- Laure Gibot, Maxime Demazeau, Véronique Pimienta, Anne-Françoise Mingotaud, Patricia Vicendo, et al.. Role of Polymer Micelles in the Delivery of Photodynamic Therapy Agent to Liposomes and Cells. Cancers, 2020, 12 (2), pp.384. ⟨10.3390/cancers12020384⟩. ⟨hal-02565671⟩
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Latest team news
Orélia Cerlati, PhD student at Softmat, defended her thesis on peptides involved in Alzheimer’s disease
Orélia carried out her research in the BIBAC and IDeAS teams at the Softmat laboratory. On 16th of December, she defended her thesis entitled: “Oxidative interactions of peptides involved in...
Faniry Andriamiseza, PhD student at Softmat, has defended her thesis on shaping supramolecular gels in an aqueous medium
Faniry carried out her research in the IDeAS team at the Softmat laboratory. On 18th of November, she defended her thesis entitled: “Shaping supramolecular gels of N-alkyl-D-galactonamides in...
3 researchers from the lab at the European Researchers’ Night
On 29th of September, Anne-Françoise Mingotaud, Orélia Cerlati and Solène Guggari, respectively researcher in the IDeAS team and doctoral students in the BIBAC and P3R teams, took part in the...