BIBAC team
The BIBAC team (“Biomolecule Interaction with Biomimetic soft matter and Analytical Chemistry”) develops analytical tools and strategies in nuclear magnetic resonance (NMR) and mass spectrometry (MS), possibly coupled with separation techniques, such as capillary electrophoresis and high-performance liquid chromatography. The team primarily focuses most of its research activities on the chemistry-biology interface.
The researchers are particularly interested in the oxidation phenomena induced by reactive oxygen species. This involves elucidating oxidation mechanisms of molecules of biological interest, studying peptide-lipid oxidative interactions and exploring the response from the metabolome to a stimulus (inflammation, oxidative stress, etc.), linked to neurodegenerative diseases.
The team also develops original analytical methodologies for the study of complex assemblies and their chemical or photochemical modification. These methodologies play a crucial role for the development of new analytical strategies.
Research topics
Analytical tools applied to oxidation phenomenon & to metabolism
Analytical methodologies for studying complex assemblies
Team members
permanent members
temporary members on average per year
Faculty staff
Engineer assistant
Team publications
This list of publications is uploaded directly from the BIBAC team’s HAL collection.
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- Chantal Galaup, Claude Picard, François Couderc, Véronique Gilard, Fabrice Collin. Luminescent lanthanide complexes for reactive oxygen species biosensing and possible application in Alzheimer’s diseases. FEBS Journal, 2021, ⟨10.1111/febs.15859⟩. ⟨hal-03240518⟩
- Sylvain Faixo, Nicolas Gehin, Stéphane Balayssac, Véronique Gilard, Sofiane Mazeghrane, et al.. Current trends and advances in analytical techniques for the characterization and quantification of biologically recalcitrant organic species in sludge and wastewater: A review. Analytica Chimica Acta, 2021, 1152, pp.338284. ⟨10.1016/j.aca.2021.338284⟩. ⟨hal-03195665⟩
- Petr Tůma, Blanka Sommerová, Dušan Koval, François Couderc. Electrophoretic Determination of Symmetric and Asymmetric Dimethylarginine in Human Blood Plasma with Whole Capillary Sample Injection. International Journal of Molecular Sciences, 2021, Capillary Electrophoresis for Amino Acids Analysis: From Analytical Development to Biomedical Application, 22 (6), pp.2970. ⟨10.3390/ijms22062970⟩. ⟨hal-03221992⟩
- Hai Yen Ta, Lucie Perquis, Cédric Sarazin, Bruno Guiard, Varravaddheay Ong-Meang, et al.. 3‐(4‐Carboxybenzoyl)quinoline‐2‐carboxaldehyde labeling for direct analysis of amino acids in plasma is not suitable for simultaneous quantification of tryptophan, tyrosine, valine, and isoleucine by CE/fluorescence. Electrophoresis, 2021, ⟨10.1002/elps.202000263⟩. ⟨hal-03139489⟩
- Thouria Bourhim, Myra Villareal, François Couderc, Abdellatif Hafidi, Hiroko Isoda, et al.. Melanogenesis Promoting Effect, Antioxidant Activity, and UPLC-ESI-HRMS Characterization of Phenolic Compounds of Argan Leaves Extract. Molecules, 2021, 26 (2), pp.371. ⟨10.3390/molecules26020371⟩. ⟨hal-03139490⟩
- Tomás Allen Rush, Virginie Puech Pagès, Adeline Bascaules, Patricia Jargeat, Fabienne Maillet, et al.. Lipo-chitooligosaccharides as regulatory signals of fungal growth and development. Nature Communications, 2020, 11, pp.3897. ⟨10.1038/s41467-020-17615-5⟩. ⟨hal-02916284⟩
- Laure Gibot, Maxime Demazeau, Véronique Pimienta, Anne-Françoise Mingotaud, Patricia Vicendo, et al.. Role of Polymer Micelles in the Delivery of Photodynamic Therapy Agent to Liposomes and Cells. Cancers, 2020, 12 (2), pp.384. ⟨10.3390/cancers12020384⟩. ⟨hal-02565671⟩
- Nathalie Pizzinat, Varravaddheay Ong-Meang, Florence Bourgailh-Tortosa, Muriel Blanzat, Lucie Perquis, et al.. Extracellular vesicles of MSCs and cardiomyoblasts are vehicles for lipid mediators. Biochimie, 2020, 178, pp.69-80. ⟨10.1016/j.biochi.2020.07.013⟩. ⟨hal-03018214⟩
- F. Collin, O. Cerlati, F. Couderc, B. Lonetti, J.-D. Marty, et al.. Multidisciplinary analysis of protein-lipid interactions and implications in neurodegenerative disorders. Trends in Analytical Chemistry, 2020, 132, pp.116059. ⟨10.1016/j.trac.2020.116059⟩. ⟨hal-03430081⟩
- Mohammad Alaeddine, Mélissa Prat, Verena Poinsot, Valérie Gouazé-Andersson, Hélène Authier, et al.. IL13-Mediated Dectin-1 and Mannose Receptor Overexpression Promotes Macrophage Antitumor Activities through Recognition of Sialylated Tumor Cells. Cancer Immunology Research, 2019, ⟨10.1158/2326-6066.CIR-18-0213⟩. ⟨hal-02194445⟩
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Latest team news
3 researchers from the lab at the European Researchers’ Night
On 29th of September, Anne-Françoise Mingotaud, Orélia Cerlati and Solène Guggari, respectively researcher in the IDeAS team and doctoral students in the BIBAC and P3R teams, took part in the...
A new mechanism for microplastics to enter the food chain
Microplastics enter plankton aggregates, which are then ingested by fish and move up the food chain. Scientists from several teams (BIBAC, IDeAS and SMODD) at the Softmat laboratory, LAAS and TBI...
Nadiia Yakovenko, PhD student at Softmat, has defended her thesis on micro- and nanoplastic pollution in the environment
Nadiia carried out her research in the BIBAC and SMODD teams at the IMRCP laboratory. On 9th December, she defended her thesis entitled: "Study of micro- and nanoplastic pollution in the...