BIBAC team
The BIBAC team (“Biomolecule Interaction with Biomimetic soft matter and Analytical Chemistry”) develops analytical tools and strategies in nuclear magnetic resonance (NMR) and mass spectrometry (MS), possibly coupled with separation techniques, such as capillary electrophoresis and high-performance liquid chromatography. The team primarily focuses most of its research activities on the chemistry-biology interface.
The researchers are particularly interested in the oxidation phenomena induced by reactive oxygen species. This involves elucidating oxidation mechanisms of molecules of biological interest, studying peptide-lipid oxidative interactions and exploring the response from the metabolome to a stimulus (inflammation, oxidative stress, etc.), linked to neurodegenerative diseases.
The team also develops original analytical methodologies for the study of complex assemblies and their chemical or photochemical modification. These methodologies play a crucial role for the development of new analytical strategies.
Research topics
Analytical tools applied to oxidation phenomenon & to metabolism
Analytical methodologies for studying complex assemblies
Team members
permanent members
temporary members on average per year
Faculty staff
Engineer assistant
Team publications
This list of publications is uploaded directly from the BIBAC team’s HAL collection.
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- Nathalie Pizzinat, Varravaddheay Ong-Meang, Florence Bourgailh-Tortosa, Muriel Blanzat, Lucie Perquis, et al.. Extracellular vesicles of MSCs and cardiomyoblasts are vehicles for lipid mediators. Biochimie, 2020, 178, pp.69-80. ⟨10.1016/j.biochi.2020.07.013⟩. ⟨hal-03018214⟩
- F. Collin, O. Cerlati, F. Couderc, B. Lonetti, J.-D. Marty, et al.. Multidisciplinary analysis of protein-lipid interactions and implications in neurodegenerative disorders. Trends in Analytical Chemistry, 2020, 132, pp.116059. ⟨10.1016/j.trac.2020.116059⟩. ⟨hal-03430081⟩
- Mohammad Alaeddine, Mélissa Prat, Verena Poinsot, Valérie Gouazé-Andersson, Hélène Authier, et al.. IL13-Mediated Dectin-1 and Mannose Receptor Overexpression Promotes Macrophage Antitumor Activities through Recognition of Sialylated Tumor Cells. Cancer Immunology Research, 2019, ⟨10.1158/2326-6066.CIR-18-0213⟩. ⟨hal-02194445⟩
- Verena Poinsot, Hai Yen Ta, Varravaddheay Ong-Meang, Lucie Perquis, Pierre Gavard, et al.. A digest of capillary electrophoretic methods applied to lipid analyzes. Electrophoresis, 2019, 40 (1), pp.190-211. ⟨10.1002/elps.201800264⟩. ⟨hal-02194453⟩
- Patricia Dubot, Jing Liang, Jacobé Dubs, Yohann Missiak, Cédric Sarazin, et al.. Sweat chloride quantification using capillary electrophoresis. Practical Laboratory Medicine, 2019, 13, pp.e00114. ⟨10.1016/j.plabm.2018.e00114⟩. ⟨hal-02194430⟩
- Dan Wang, François Couderc, Chang Fu Tian, Wenjie Gu, Li Xue Liu, et al.. Conserved Composition of Nod Factors and Exopolysaccharides Produced by Different Phylogenetic Lineage Sinorhizobium Strains Nodulating Soybean. Frontiers in Microbiology, 2018, 9 (2852), pp.1-14. ⟨10.3389/fmicb.2018.02852⟩. ⟨hal-02194479⟩
- Audrey Ric, Vincent Ecochard, Jason S. Iacovoni, Audrey Boutonnet, Frédéric Ginot, et al.. G-quadruplex aptamer selection using capillary electrophoresis-LED-induced fluorescence and Illumina sequencing. Analytical and Bioanalytical Chemistry, 2018, 410 (7), pp.1991-2000. ⟨10.1007/s00216-018-0865-5⟩. ⟨hal-02194924⟩
- Myriam Hayder, Matteo Garzoni, Davide Bochicchio, A.-M. Caminade, François Couderc, et al.. Three-dimensional directionality is a pivotal structural feature for the bioactivity of azabisphosphonate-capped poly(PhosphorHydrazone) nanodrug dendrimers. Biomacromolecules, 2018, 19 (3), pp.712-720. ⟨10.1021/acs.biomac.7b01398⟩. ⟨hal-01957988⟩
- Verena Poinsot, Varravaddheay Ong-Meang, Audrey Ric, Pierre Gavard, Lucie Perquis, et al.. Recent advances in amino acid analysis by capillary electromigration methods: June 2015-May 2017. Electrophoresis, 2018, 39 (1), pp.190-208. ⟨10.1002/elps.201700270⟩. ⟨hal-02194932⟩
- Audrey Ric. Caractérisation d'aptamères par électrophorèse capillaire couplée au séquençage haut-débit Illumina. Chimie organique. Université Paul Sabatier - Toulouse III, 2017. Français. ⟨NNT : 2017TOU30388⟩. ⟨tel-02301523⟩
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Latest team news
Orélia Cerlati, PhD student at Softmat, defended her thesis on peptides involved in Alzheimer’s disease
Orélia carried out her research in the BIBAC and IDeAS teams at the Softmat laboratory. On 16th of December, she defended her thesis entitled: “Oxidative interactions of peptides involved in...
Faniry Andriamiseza, PhD student at Softmat, has defended her thesis on shaping supramolecular gels in an aqueous medium
Faniry carried out her research in the IDeAS team at the Softmat laboratory. On 18th of November, she defended her thesis entitled: “Shaping supramolecular gels of N-alkyl-D-galactonamides in...
3 researchers from the lab at the European Researchers’ Night
On 29th of September, Anne-Françoise Mingotaud, Orélia Cerlati and Solène Guggari, respectively researcher in the IDeAS team and doctoral students in the BIBAC and P3R teams, took part in the...